On the mechanism of action of clonidine - Europe PMC Article -.
FULL TEXT Abstract 1 Noradrenaline and clonidine were applied by microiontophoresis to single neurones in the cerebral cortex and medullary reticular. On Feb 1, 1974 R. Bloch and others published The mechanism of action of clonidine Intravenous administration of clonidine. Studies on the mechanism of methyl-dopa. Evidence for a central postsynaptic action of clonidine.
CENTRALLY ACTING AGENTS
Mechanism of action. Clonidine can cause sedation and drowsiness. Centrally acting agents are no longer used widely because of poor side effect profiles. Br. J. Pharmac. 1974, 51, 359-365 ON THE MECHANISM OF ACTION OF CLONIDINE EFFECTS ON SINGLE CENTRAL NEURONES CAROLINE ANDERSON &T. W. STONE Department of Physiology.