Phenytoin Pharmacokinetics and bioavailability - Wiley Online Library
The absolute bioavailability of an oral dosage form Dilantin Kapseals varied. AUC 0. x area under the plasma concentration-time curve, calculated from. Winter-Tozer equation is useful in predicting normalized phenytoin. in the rate of phenytoin metabolism, which increase plasma drug concentration and. Phenytoin Half-Life and Clearance during Maintenance Therapy in Adults and. of recommended daily dosing of phenytoin and calculations of dosing changes.
Phenytoin/Dilantin Correction for Albumin / Renal Failure - MDCalc
The Phenytoin Correction for Albumin / Renal Failure calculates correct phenytoin dosing based on albumin levels and/or renal failure. Related Calcs. Ca Correction for Albumin · Corrected QT QTc · Have feedback about this calculator? Calculations used. Phenytoin follows saturation kinetics non-linear - therefore maintenance dose R can be given by. where. Km = 5.7mg/L Adults or.