Ketoconazole and sulphaphenazole as the respective selective.
The potential of ketoconazole and sulphaphenazole to inhibit specific P450. 6β-hydroxylase activities, with mean IC50's of 0.19 and 0.22 μM respectively. It is used to treat fungal infections of the skin ringworm, athlete's foot, and jock itch and nails. It is also used to treat "sun fungus" tinea versicolor, pityriasis versicolor. Each gram of white, odourless cream contains ketoconazole 20 mg 2%. Ketoconazole - CAS 65277-42-1 - Calbiochem MSDS material safety data sheet or SDS. Also acts as an inhibitor of 5-lipoxygenase 5-LO; IC50 = 26 µM and.
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Days ago. Buy Ketoconazole Overnight Shipping No Prescription. Order Ketoconazole Online And Save Your Money. Ic Ketoconazole 200 Mg Ketoconazole is a 50/50 racemic mixture of two enantiomers 2S,4R and 2R,4S. and CYP21 IC50 1000nM, 10x in cell lines expressing recombinant human. Ketoconazole inhibited whole-cell HERG current IHERG with a clinically relevant half-maximal inhibitory drug concentration IC50 value of 1.7 μM.
Ketoconazole - CAS 65277-42-1 - Calbiochem CAS. - EMD Millipore
Sirolimus oral absorption in rats is increased by ketoconazole but is not. polarized basolateral-to-apical flux of rhodamine 123 with an IC50 of 0.625 to 1.25. In human hepatocytes, ketoconazole dose dependently inhibited the formation of N+-glucuronides 50% inhibitory concentration IC50, 1.5 μM, while rifampin.
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Ketoconazole is used to treat serious fungal or yeast infections, such as candidiasis thrush, oral thrush, blastomycosis Gilchrist's disease, coccidioidomycosis. Jun 29, 2017. Ketoconazole was much less toxic to macrophage than antimony Fig 1B; IC50 = 436.5 vs. 7.3 μM; ketoconazole vs. antimony presenting.