Eliminate the CAUSE of the headaches or migraines, dont jsut cover.
Patients should be informed that amitriptyline Elavil, for instance, is also used for depression, usually. Topamax is FDA approved as a migraine preventive. Oct 27, 2016. The CHAMP trial of amitriptyline and topiramate vs placebo was stopped early for futility, leaving experts to consider how to proceed. BETA-BLOCKERS without intrinsic sympathomimetic activity, amitriptyline, divalproex sodium/sodium valproate, and topiramate are the most effective drugs for.
Chronic Daily Headache Diagnosis and Management - American.
Apr 15, 2014. Pharmacologic therapies include amitriptyline, gabapentin, onabotulinumtoxinA, propranolol, tizanidine, topiramate, and valproate. 9% absolute difference in headache-free days vs. placebo; average of 4-hour reduction in. Apr 18, 2013. Pooled analysis showed no differences in treatment discontinuation with topiramate versus amitriptyline Table C. Individual unique RCTs.