Loratadine - DrugBank
Jun 13, 2005. Loratadine is a derivative of azatadine and a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and. Desloratadine is the major active metabolite of loratadine and possesses qualitatively similar pharmacodynamic activity. LD50 values after oral administration. So successfully with loratadine; the LD50 approximately half of a lethal dose seems to range from about 500mg/kg to a few thousand mg/kg.
Such a thing as anti-histamine overdose? - Straight Dope Message Board
Health. Desloratadine tablets are contraindicated in patients who are hypersensitive to this medication or to any of its ingredients or to loratadine. Environment. Dec 17, 2014. Loratadine. SAFETY DATA SHEET according to Regulation EC No. 1907/2006 as amended by EC No. 1272/2008. 15625. 1.1 Product Code.
Product Monograph Template - Standard - Bayer
Jun 27, 2016. Loratadine Orally Disintegrating Tablets USP 10 mg. In male and female rats, the intraperitoneal LD50 values were determined to be 5134. Safety isn't an issue either to anyone wondering as the LD50 for Loratadine seems to be around 450-500mg for humans and SWIM only plans.